Mercury is a hazardous substance that has unique neurodevelopmental toxic effects in humans.However, the precise sequence of molecular events read more that culminate in Hg-induced neuropathology is still unknown.Though the omics studies have been generating an enormous amount of new data about Hg toxicity, our ability to interpret such a large qua
Human activities, such as mining, forestry, and agriculture, strongly influence processes in natural systems.Because conservation has focused on managing and protecting wildlands, research has focused on understanding the indirect influence of these human activities on wildlands.Although a conservation focus on wildlands is critically important, th
Objective: To assess the potential risk of dengue transmission in a non-endemic city using a spatial epidemiological approach.Methods: Past dengue exposure of the general population was examined by read more dengue virus (DENV) IgG testing of archived samples from voluntary blood donors.Vector intensities were determined by local ovitrap index (OI)
Cyclin D1 regulates G1 progression.Its transcriptional regulation is well understood.However, the mechanism underlying cyclin D1 ubiquitination and its subsequent degradation is not yet clear.We report that cyclin D1 undergoes increased degradation in the cytoplasm during S phase in a variety of cancer cells.This is mediated by phosphorylation at T